International Journal of Paediatrics and Geriatrics

International Journal of Paediatrics and Geriatrics

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2024, Vol. 7, Issue 1, Part A

The percentage of hemoglobin Bart’s among group of neonates in Al-Najaf City
Author(s)
Haider Musa Kaream, Mahir Mohammed Ali Altaher and Talib Abdul Jaleel Al Madany
Abstract
Background: Alpha-thalassemia is caused by deletions of the α-globin genes on chromosome 16. The presence of hemoglobin Bart’s on the newborn screen almost always indicates that one or more of the baby’s α-globin genes are deleted.
Objectives: To identify the rate of occurrence of HbBart’s among group of neonates by cord blood assay.
Materials and Methods: Total of 120 cord blood samples of newborn were examined by α-thalassemia short program utilizes the principles of cation exchange HPLC for the presence of Hb Bart’s. Statistical analysis utilized SPSS 26.
Results: Hb Bart’s was encountered in 93 cases (77.5%) neonates constituting 1 - 10.4% of their total Hb, of these 92 cases (76.67%) were of α-thalasse-2 (Silent alpha-thalassemia) and 1 (0.83%) of α-thalasse-1 (α-thalassemia trait). Our results found to be slightly higher than the prevalence of the disease in the Middle East and western Asia (12.55%) and Southeast Asia (6 -75%).
Conclusion: Our study clarifies the importance for further future study and follow up of neonates with high percentage of HbBart’s.
Pages: 07-12 | Views: 319 | Downloads: 158


International Journal of Paediatrics and Geriatrics
How to cite this article:
Haider Musa Kaream, Mahir Mohammed Ali Altaher, Talib Abdul Jaleel Al Madany. The percentage of hemoglobin Bart’s among group of neonates in Al-Najaf City. Int J Paediatrics Geriatrics 2024;7(1):07-12. DOI: 10.33545/26643685.2024.v7.i1a.215
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