Acute kidney injury (AKI) is defined as rapid deterioration of renal function resulting in retention of nitrogenous wastes and inability of kidney to regulate fluid and electrolyte homeostasis.
Objective: To determine the electrolyte abnormalities in Acute Kidney Injury in children admitted in PICU.
Setting: This study was conducted in all patients within the age group of 1 month to 18 years admitted in the PICU (Pediatric Intensive Care Unit) at Basaveshwar teaching and General hospital and Sangameshwar hospital attached to Mahadevappa Rampure medical college during a period from December 2015 to May 2017.
Result: There were 40(58.0%) male AKI cases and 29(42.0%) female AKI cases in the study. The sex ratio of total study cases of Male to Female was 1.4:1 The sex ratio of AKI cases of Male to Female was 1.38:1. Statistically very highly significant difference of Anuria, Gross hematuria and Encephalopathy among AKI and Non-AKI groups (P<0.001) and there were statistically significant differences of Vomiting, Loose motion among AKI and Non-AKI groups (P<0.05). The symptoms of Anuria, Gross hematuria, Encephalopathy, Vomiting and Loose motion were significantly less in the non-AKI cases as compared to AKI cases. There were no statistical significant difference of Oliguria, Fever, Seizures, Breathlessness and Gl. Hemorrhage among AKI and Non-AKI groups (P>0.05).
Conclusion: It was concluded that AKI was associated with increased mortality (p<0.000).mortality rate was 34.8% compared to non AKI. In the present study, mortality was 9.1%in Stage 1 and 28.5% in Stage 2. Stage 3 it is 43.3%. Mortality was high in stage 3. In the present study, the median duration of PICU and Hospital stay was 9.98±7.27 in AKI group compared to7.41 ± 5.62 days in Non AKI group (p<0.001).