International Journal of Paediatrics and Geriatrics

International Journal of Paediatrics and Geriatrics

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International Journal of Paediatrics and Geriatrics

2020, Vol. 3, Issue 2, Part C

Incidence of congenital hypothyroidism and associated congenital anomalies at VSS Medical College & Hospital, Burla
Author(s)
Vidhyadhara Naik TL, Sanjaya Kumar Jena and Nihar Ranjan Mishra
Abstract
Background: The worldwide incidence of CH ranges from 1 in 3000 to 1 in 4000 live newborn. However, varied incidence has been found from state, regional, and national screening programs.
Objective: to know the incidence of Congenital Hypothyroidism and associated congenital anomalies in this part of the country, which is necessary to understand the burden of congenital hypothyroidism to the society.
Setting: Primary serum TSH measurement in screening neonates with backup thyroxine (T4) determination in infants with high TSH levels (>20mIU/L). TSH and FT4 were estimated by Chemi Luminescence Immuno Assay (CLIA) method using reagent moonblind, INC.
Result: Serum TSH of screened neonates ranged between 0.16mIU/L and 80.32mIU/L, Mean ± SD of sTSH being 5.80±3.96mIU/L. Out of 2212 screened newborns, 9 newborns had sTSH value >20mIU/L. out of 9 recalled newborns, 3 had persistently elevated sTSH >20mIU/L. Making incidence of Congenital hypothyroidism of 1:737 in our study. In a study carried out at Israel found 15.6% cases of Congenital Hypothyroidism were associated with congenital anomalies majority being cardiac anomalies.
Conclusion: In our study we found a higher incidence of 1 in 737, when compared to estimated national incidence of congenital hypothyroidism. Our study reported significant number of neonates with sTSH value >10mIU/L indicating iodine deficiency prevalent in this part of country.
Pages: 157-161 | Views: 312 | Downloads: 153
How to cite this article:
Vidhyadhara Naik TL, Sanjaya Kumar Jena, Nihar Ranjan Mishra. Incidence of congenital hypothyroidism and associated congenital anomalies at VSS Medical College & Hospital, Burla . Int J Paediatrics Geriatrics 2020;3(2):157-161. DOI: 10.33545/26643685.2020.v3.i2c.111
International Journal of Paediatrics and Geriatrics