2020, Vol. 3, Issue 1, Part A
Comparative analysis of serum vitamin d level in under five aged children with acute lower respiratory tract infection: A case-control study
Author(s)
Bhavani KC, Virendra Kumar Gupta, Bhagwan Sahai Natani, Rupesh Masand and Chaman Ram Verma
Bhavani KC, Virendra Kumar Gupta, Bhagwan Sahai Natani, Rupesh Masand and Chaman Ram Verma
Abstract
Background: Vitamin D has been associated with the immune functions acting at the cell level and being involved with induction of different cells of immune system. It plays a major role in lung growth & function, which prevents infections of respiratory tract. Methods: Hospital based prospective, observational, case control study was conducted in the Department of Pediatrics National Institute of medical Science and research, Jaipur, Rajasthan, from January 2017 to june 2018. A total of 250 children aged 1 to 5 years in each group with & without ALRI, who fulfilled the inclusion criteria were included and Vitamin D levels were measured. Results: In 250 cases mean age were 3.190 1.24, 55.2% were males and 44.8% females. 60% of cases and 54% of control were from rural areas. Among cases 17.6% had insufficient and 64.4% had deficient vitamin D status whereas in control group 64.4% had normal, 22.8% insufficient and only 12.8% had deficiency of vitamin D. Highly significant p-value was obtained. 56.4% of cases had low serum calcium levels. Mean vitamin D levels was 19.9 11.46 in cases and 33.2112.30 in controls. Mean serum vitamin D of 16.9 in urban and 19 in rural area in cases whereas 30.6 and 35.3 in urban and rural areas respectively in control group. Conclusions: We found a strong correlation of vitamin D deficiency with ALRI. Empirical supplementation of vitamin D can prevent the incidence of these infections. We can add Vitamin D in different public health programs.
Background: Vitamin D has been associated with the immune functions acting at the cell level and being involved with induction of different cells of immune system. It plays a major role in lung growth & function, which prevents infections of respiratory tract. Methods: Hospital based prospective, observational, case control study was conducted in the Department of Pediatrics National Institute of medical Science and research, Jaipur, Rajasthan, from January 2017 to june 2018. A total of 250 children aged 1 to 5 years in each group with & without ALRI, who fulfilled the inclusion criteria were included and Vitamin D levels were measured. Results: In 250 cases mean age were 3.190 1.24, 55.2% were males and 44.8% females. 60% of cases and 54% of control were from rural areas. Among cases 17.6% had insufficient and 64.4% had deficient vitamin D status whereas in control group 64.4% had normal, 22.8% insufficient and only 12.8% had deficiency of vitamin D. Highly significant p-value was obtained. 56.4% of cases had low serum calcium levels. Mean vitamin D levels was 19.9 11.46 in cases and 33.2112.30 in controls. Mean serum vitamin D of 16.9 in urban and 19 in rural area in cases whereas 30.6 and 35.3 in urban and rural areas respectively in control group. Conclusions: We found a strong correlation of vitamin D deficiency with ALRI. Empirical supplementation of vitamin D can prevent the incidence of these infections. We can add Vitamin D in different public health programs.
Pages: 28-31 | Views: 1745 | Downloads: 843
How to cite this article:
Bhavani KC, Virendra Kumar Gupta, Bhagwan Sahai Natani, Rupesh Masand, Chaman Ram Verma. Comparative analysis of serum vitamin d level in under five aged children with acute lower respiratory tract infection: A case-control study. Int J Paediatrics Geriatrics 2020;3(1):28-31. DOI: 10.33545/26643685.2020.v3.i1a.56
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