2018, Vol. 1, Issue 1, Part A

Materials and Methods:The study was done at the Department of Paediatrics, Madha Medical College and Research Institute, Chennai, India, the people who took part in the study were between the ages of 4 and 15. This study was conducted at the May 2017 to April.2018. For the study, 50 steady asthmatics who only needed a bronchodilator were chosen. 32 of these patients were given budesonide every day for a year, while the other patients were given a fake drug. During the study, 50 kids between the ages of 4 and 15 who did not use steroids took part.

Results: Long-term treatment with budesonide resulted in a significant reduction in airway hyperresponsiveness. There was a noticeable improvement in lung function parameters. A decrease in the frequency of asthma exacerbations and emergency visits was observed. Overall clinical asthma symptoms, including coughing and wheezing, were significantly reduced, leading to better asthma control. The treatment was well-tolerated with minimal side effects, and adherence to the prescribed inhaler regimen was high.

Conclusions: According to the results, long-term inhaled steroid treatment can cause a big drop in airway hyperresponsiveness and even complete remission in some cases. These gains have been linked to clinically significant improvements in asthma in children.