International Journal of Paediatrics and Geriatrics

International Journal of Paediatrics and Geriatrics

Journal is inviting manuscripts for its coming issue. Contact us for more details.

International Journal of Paediatrics and Geriatrics

2020, Vol. 3, Issue 1, Part C

Memory problems and weight loss: A case report
Author(s)
Karavadra B and Gunawardena I
Abstract
This interesting case report illustrates a paraneoplastic syndrome presenting as dementia. A 75-year-old Malaysian lady with a 45-pack year smoking history presented with unintentional weight loss of three stone in three months with generalised aches and pains and short-term memory problems. Her inflammatory markers were raised, liver function tests were deranged, and her thyroid stimulating hormone was low. Cerebrospinal fluid examination revealed a mild increase in protein. On the Addenbrookes Cognitive Scale her score was 39/100 and she also had clinical features to suggest mild depression. A Computed Tomography of the thorax showed a 34mm mass anterior to the trachea and an enlarged right para-tracheal lymph node. Subsequent endo-bronchial ultrasound biopsy confirmed metastatic small-cell lung cancer. She had positive autoantibodies for anti-Hu and anti-Sox 1; indicating a paraneoplastic syndrome or limbic encephalitis. Paraneoplastic syndromes are rare and difficult to diagnose. In this case, the paraneoplastic manifestations mimicked a dementia illness.
Pages: 155-157 | Views: 101 | Downloads: 52
How to cite this article:
Karavadra B and Gunawardena I. Memory problems and weight loss: A case report. International Journal of Paediatrics and Geriatrics. 2020; 3(1): 155-157. DOI: 10.33545/26643685.2020.v3.i1c.74
International Journal of Paediatrics and Geriatrics